Prevalence of Hepatitis B and C Virus Infection among Students of a Private Tertiary Institution in South-Western Nigeria

Main Article Content

Seyi Samson Enitan
Olayimika Kehinde Adebola
Esther Ngozi Adejumo
Grace Elejo Itodo
Emmanuel Ileoma
Adeolu Sunday Oluremi
Damilola Omotola

Abstract

Background: Hepatitis B virus (HBV) and hepatitis C virus (HCV) infection is a major health problem and account for a substantial proportion of liver diseases worldwide.

Aim: The aim of this study was to determine the prevalence rate of Hepatitis B and C virus infection among undergraduate students of Babcock University.

Methodology: The blood samples of 200 participants (96 males and 104 females) were randomly collected and screened using rapid serological methods. HBV markers were determined using a HBV 5 in 1 Panel cassette (Innovita Biological Technology Co., Ltd., China); while antibody to HCV was detected using anti-HCV test strip (Blue Cross Bio-Medical Co., Ltd., China). The demographic and clinical information of the participants were collected using structured questionnaires.

Results: Out of the 200 participants screened, 3 (1.5%) were positive for HBsAg, 10 (5.0%) were positive for HBsAb, 3 (1.5%) were positive for HBcAb, 2 (1.0%) were positive for HBeAb and none (0%) was positive for HBeAg. 2 (2.1%) of the 96 males screened were positive for HBsAg, while only one (1%) out of the 104 females screened was positive for HBsAg. There was no significant difference (P>0.05) between the number of male and female students positive for HBsAg. On the basis of age distribution, data show that 3 (2.7%) out of the 110 students that were 16-20 years old were positive for HBsAg, while students in the other age groups were negative for HBsAg. Risk factors associated with infection include: tattooing, history of blood transfusion and shared sharp objects. Interestingly, zero prevalence rate (0%) of HCV mono-infection, as well as HBV/HCV co-infection was recorded in this current study.

Conclusion: The outcome of this study showed that a low prevalence rate of HBV mono-infection exists among undergraduate students of Babcock University, therefore the on-going public health campaign programme against Hepatitis B and C should be sustained.

Keywords:
Liver disease, hepatitis, HBsAg, HBsAb, HBcAb, HBeAb, HBeAg, anti-HCV Ab

Article Details

How to Cite
Enitan, S., Adebola, O., Adejumo, E., Itodo, G., Ileoma, E., Oluremi, A., & Omotola, D. (2019). Prevalence of Hepatitis B and C Virus Infection among Students of a Private Tertiary Institution in South-Western Nigeria. International Journal of TROPICAL DISEASE & Health, 36(3), 1-15. https://doi.org/10.9734/ijtdh/2019/v36i330144
Section
Original Research Article

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