International Journal of TROPICAL DISEASE & Health https://journalijtdh.com/index.php/IJTDH <p style="text-align: justify;"><strong>International Journal of TROPICAL DISEASE &amp; Health (IJTDH) (ISSN: 2278 – 1005)</strong> aims to publish&nbsp;high quality papers (<a href="/index.php/IJTDH/general-guideline-for-authors">Click here for Types of paper</a>)&nbsp;in the areas of tropical medicine and public health research, reports on the efficacy of new drugs and methods of treatment, prevention and control methodologies, new testing methods and equipment. This is a quality controlled, peer-reviewed, open access INTERNATIONAL journal. IJTDH will not only publish traditional full research reports, including short communications, but also this journal will publish reports/articles on all stages of the research process like study protocols, pilot studies and pre-protocols. IJTDH is novelty attracting, open minded, peer-reviewed medical periodical, designed to serve as a perfectly new platform for both mainstream and new ground shaking works as long as they are technically correct and scientifically motivated. This journal has no connection with any society or association, related to Tropical medicine, disease or Public health and allied fields. This is an independent journal.</p> <p style="text-align: justify;">This is an open access journal which means that all content is freely available without charge to the user or his/her institution. Users are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author. This is in accordance with the BOAI definition of open access.</p> SCIENCEDOMAIN international en-US International Journal of TROPICAL DISEASE & Health 2278-1005 Neglected Tropical Diseases of Public Health Importance in India: Current Status and the Way Ahead https://journalijtdh.com/index.php/IJTDH/article/view/30644 <p><strong>Introduction: </strong>In global health, critical challenges have erupted from infectious diseases, including the emergence and re-emergence of old and new infectious diseases. This is directly attributed to rapid human development including massive demographic changes, increasing population, and environmental degradation to name a few. Despite tremendous advances in the health of its citizens who live below the poverty line, India bears a disproportionately high burden of neglected tropical diseases with over half of the 20 WHO classified neglected tropical diseases at endemic levels. In a global fight against these diseases, India occupies a unique place as a country that despite being deeply affected by these devastating and deadly illnesses, also holds solutions on how innovation might eliminate these ancient maladies.</p> <p><strong>Aims and Objectives: </strong>The present article reviews the common neglected tropical diseases of India, their magnitude and current status with respect to interventions for their control, challenges in the path of their elimination and the comprehensive all-inclusive approaches that can be adopted to curb the tropical disease burden of the Indian sub-continent.</p> <p><strong>Methodology: </strong>The present study is literature review. PubMed, EMBASE and Scopus databases were searched using the key words “ neglected tropical diseases”, “infectious diseases”, “treatment of tropical diseases” and their MeSH terms in any possible combination using the logical operators “AND” and “OR”. The reference list of all the studies was screened to identify other studies of interest. The search was reiterated until July 2021.</p> <p><strong>Results: </strong>Though the progress towards elimination of neglected tropical diseases is already underway, a concerted strategy is needed to assist the elimination efforts for these diseases. An all-inclusive policy to foster research and innovation in drug discovery, diagnostics, and vaccine development in neglected tropical diseases is lacking. There is also an absence of structured training of healthcare workers to improve their skills and capacity in disease management in endemic and disease prone areas.</p> <p><strong>Conclusion: </strong>To obtain the high objective of improving health and reducing vulnerabilities, it is important that healthcare workers and professionals from other backgrounds bind together to broaden the perspectives that are needed to address. There is a call for a comprehensive policy for neglected diseases research in India to foster drugs, diagnostics, and vaccine innovation, critical for evolving needs for elimination programs.</p> Vikramaditya Rai ##submission.copyrightStatement## 2022-08-06 2022-08-06 17 24 10.9734/ijtdh/2022/v43i1530644 ‘Spread’ of Artemisinin Resistance in Myanmar Revisited https://journalijtdh.com/index.php/IJTDH/article/view/30643 <p>Geostatistical models have been widely used to represent disease prevalence in spatial disease mapping. More recently, these models have been employed to estimate geographic ‘spread’ of artemisinin resistance (AR) in South East Asia from genetic mutations identified in the K13 gene of the malaria <em>Plasmodiumfalciparum</em> parasite. Here, I revisit the question of ‘spread’ of AR as represented by resistant <em>plasmodiumfalciparum</em> in Myanmar, when re-evaluated from K13 mutant alleles data published by Tun et al. [1]. The new analysis gives a broader perspective by incorporating information published by the World Health Organization (WHO) in 2015 and subsequently in 2018 of the K13 mutant alleles confirmed to confer or to be associated with artemisinin resistance. This provides insights which hitherto have not been described and reveals the disparity between the estimation of ‘spread’ of AR by Tun et al. [1] and that of AR prevalence based on metrics which are supported by published WHO data.</p> Eric P. M. Grist ##submission.copyrightStatement## 2022-08-01 2022-08-01 1 16 10.9734/ijtdh/2022/v43i1530643 Clinical Characteristics and Etiology of Chronic Liver Disease among Egyptian Patients in Nile Delta: A Clinical Study https://journalijtdh.com/index.php/IJTDH/article/view/30645 <p><strong>Background: </strong>Chronic liver disease (CLD) is an extremely common clinical condition that causes significant morbidity and mortality and was responsible for 1.3 million deaths worldwide. There had been a 46% increase in CLD mortality in the world between 1980 and 2013 and most of this increase has been reported in low-income countries in Asia and Africa including Egypt. These countries are experiencing a demographic and epidemiologic transition in disease burden and Egypt is one of the epicenters of this change. Previously, CLD in Egypt was traditionally attributed to schistosomiasis mainly in the region of the Nile Delta until the mid-1980s.</p> <p><strong>Aims:</strong> To capture the modes of clinical presentation and at which stage CLD patients seek clinical care, as well as the dramatic change in the etiological profile of CLD in this area of the Nile Delta</p> <p><strong>Methods:</strong> 1013 newly diagnosed CLD patients were selected and identified from the Tanta Liver Center (TLC) across the middle of the Nile Delta. After informed or written consent, all consecutive patients (18 years and above) referred to TLC with suspected or overt chronic liver disease were subjected to full history taking, clinical examination searching for stigmata of chronic liver disease, and laboratory studies including urine, blood sugar, liver biochemical tests (bilirubin, ALT, AST&amp; serum albumin), prothrombin, viral markers (HCV Ab &amp; HBS Ag) and AFP. Imaging studies including the abdominal US for all patients and triphasic CT and liver biopsy in selected patients.</p> <p><strong>Results: </strong>About 50% of our CLD patients present at a relatively advanced stage of decompensated cirrhosis (ascites in 39.2%, bleeding in 22.8%, and HCC in 9.3%).</p> <p>CLD patients of schistosomal etiology presented mainly with manifestations of portal hypertension (splenomegaly, UGI Bleed &amp; thrombocytopenia) that was significantly higher than the other 2 groups.</p> <p>The vast majority of our CLD patients (83.5%) have viral etiology, while only 11.1% have schistosomal etiology and the remaining 5.4% have non-identified etiology.</p> <p><strong>Conclusion:</strong> based on the results of the present study, it is evident that HCV had replaced schistosomiasis as the predominant cause of CLD in Egypt particularly in the region of the Nile Delta. The late presentation of a good percentage of our CLD patients raises the importance of screening programs for CLD in this endemic area of the Nile Delta.</p> Mortada M. Abd-Elrazek Nashwa M. El-Gharabawy Samir A. Atlam Mamdouh A. Gabr ##submission.copyrightStatement## 2022-08-09 2022-08-09 25 35 10.9734/ijtdh/2022/v43i1530645 New Advances in Diabetes Care Group Education Research https://journalijtdh.com/index.php/IJTDH/article/view/30646 <p><strong>Objective:</strong> This study aims to evaluate the effectiveness of health education in diabetes.</p> <p><strong>Methods:</strong> This study investigated 40 diabetic patients treated in a tertiary A hospital from February 2022 to May 2022 through convenient nearby sampling. Eligible patients were evaluated by the general basic information questionnaire, diabetes self-behavior management scale through the number of lectures.</p> <p><strong>Results:</strong> Through the questionnaire survey, it was found that the average self-behavior management score of patients who have been in diabetes care group was 63.3, which was much higher than the 41.3 points for patients without group education. And patients participating in diabetes group education scored higher than those who did not participate in group education in terms of diet, exercise, and foot care.</p> <p><strong>Conclusion: </strong>Group education can improve the self-behavior management ability of diabetic patients.</p> Ling Zhang HongMei Liu Jing Zhang Qian Niu ##submission.copyrightStatement## 2022-08-10 2022-08-10 36 44 10.9734/ijtdh/2022/v43i1530646