Open Access Case Report

Respiratory Syncytial Virus-associated Rhabdomyolysis and Sensorineural Hearing Loss in a Healthy Adult: A Case Report

Tongluk Teerasarntipan, Pannawadee Uppathamnarakorn

International Journal of TROPICAL DISEASE & Health, Page 1-5
DOI: 10.9734/IJTDH/2017/31968

Aims: This article aimed to demonstrate rare extra-pulmonary complications resulted from the respiratory syncytial virus infection (RSV) in healthy adult. We also performed a literature review about the treatment experience from these complications.

Presentation of Case: We examined a 33-year-old healthy Thai man, who initially had RSV pharyngitis that was later developed into rhabdomyolysis and sensorineural hearing loss. The complications recovered without permanent organ damage after treatment with intravenous fluid and prednisolone.

Discussion: Rhabdomyolysis and sensorineural hearing loss are considerably rare complications from RSV infection. According to the literature review and experience from our case, patients with extra-pulmonary complications have relatively good prognosis. Most patients were treated by intravenous fluid and corticosteroid in some case.

Conclusion: Although RSV-associated rhabdomyolysis and sensorineural hearing loss are rare, supportive treatment without RSV-specific antiviral drug is sufficient to treat these complications.

Open Access Original Research Article

Influence of Substituents on the Antiplasmodial and Cytotoxic Activities of 5-chloro-3,4-dihydro-1H-pyrano[3,4-b]-1,10-phenanthrolinone as Antimalarial Agent

Cheikh Sall, Samba Fama Ndoye, Matar Seck, Alexis Valentin, Yves Blache

International Journal of TROPICAL DISEASE & Health, Page 1-7
DOI: 10.9734/IJTDH/2017/31322

Background: Malaria is one of the most common parasitic disease in tropical and subtropical regions. Plasmodium falciparum, one of the causative agent of malaria is resistant to many type of antimalarial drugs. This study present in vitro assessment of the antiplasmodial activity of substituted phénanthrolinone compounds.

Methods: A series of 7 substituents were used to substitute the chlorine on the 5 position in the 5-chloro-3,4-dihydro-1H-pyrano[3,4-b]-1,10-phenanthrolinone ring. In vitro antiplasmodial activities were evaluated on chloroquine-sensitive and resistant strains of P. falciparum.

Results: The results showed that compounds 7 and 8 possessing N,N-diethylamino side chain had the best antiplasmodial activities. In addition, the cytotoxic activities were evaluated on HeLa cells and compound 8 was the least cytotoxic of all studied compounds.

Conclusion: The synthesis and antimalarial activity of substituents of compound 2 were carried out. This study has shown that compounds with basic and lipophilic substituents exhibited the best antiplasmodial activity.

Open Access Original Research Article

Perception and Satisfaction of Employees with National Health Insurance Scheme Services: A Descriptive Study at University College Hospital, Ibadan, Nigeria

Iyabode Adetoro Gbadamosi, Esther Oluwatoyin Famutimi

International Journal of TROPICAL DISEASE & Health, Page 1-12
DOI: 10.9734/IJTDH/2017/29019

Aim: To assess perception and satisfaction of employees with National Health Insurance Scheme (NHIS) Services and to ensure quality NHIS services for all employees in health institutions in Nigeria.

Study Design: Descriptive cross-sectional design.

Place and Duration of Study: Department of Clinical Nursing, Department of Physiotherapy, Department of Health Information Management, Department of Medicine, Department of Medical Laboratory, Department of Administration Services, Department of Accounting, Department of Engineering, Department of Public Relation, Department of Social Work and Department of Radiography, at University College Hospital (UCH), Ibadan Nigeria between February 2016 and March 2016.

Methodology: Three hundred and fifty eligible employees in the study setting completed a self-administered questionnaire. Knowledge of respondents with NHIS; problems encountered by respondents during registration with NHIS; respondents’ perception of NHIS services; factors hindering effective utilization of NHIS services by respondents and satisfaction of respondents with NHIS services were assessed. Chi-Square test was used to determine relationships between variables.

Results: One hundred and sixty-two (46.3%) males and 188 (53.7%) females participated in the study with 82% response rate. Their mean age was 34.6±1.7. Level of Significance was set at = .05. Only 51.4% had good knowledge while 48.6% had poor knowledge about NHIS program. Forty-two percent and 20% of respondents rated NHIS services as good and excellent respectively. Meanwhile, 48.6% respondents were satisfied with the services of the scheme. Respondents’ ethnicity was not significant with their perception of NHIS services and gender was also not significant with their level of satisfaction with NHIS services.

Conclusion: Satisfaction with NHIS services was low at UCH, Ibadan, Nigeria. This may result to under utilization of the scheme, poor health status and low productivity among the employees of this institution. However, further study needed to be done to explore the opinions of employees on the way forward.

Open Access Original Research Article

“College Students’ Perception of Their Parents’ Style of Parenting in Enugu and Abakiliki, South-East Nigeria

A. R. C. Nwokocha, V. Onukwuli, J. M. Chinawa, A. Ubesie, P. C. Manyike, E. Aniwada, A. T. Chinawa

International Journal of TROPICAL DISEASE & Health, Page 1-8
DOI: 10.9734/IJTDH/2017/31309

Background: Adolescents’ college students perception of their parents’ style of parenting has taken diverse forms in different societies/cultures and this may impact on their psychosocial development.

Methods: This is a cross sectional study which accessed adolescent college students’ perception of their parents’ styles of parenting. Using simple random sampling the students were selected in proportion with the size of the class. This study assessed the “college students’ perception of their parents’ style of parenting in Enugu and Abakiliki, South-East Nigeria.

Data was analyzed using SPSS version 19. Chi-square was used to test significant association of categorical variables.

Results: A total of eight hundred and twenty eight adolescent college students aged 10-19 years with a mean age, 13.8 ± 1.5 years comprising four hundred and ninety (59.2%) males and 338 (40.8%) females completed the questionnaire. Three hundred and sixty one (43.6%) respondents reported having an autocratic parent while 206 (24.9%) and 227(27.4%), reported permissive, authoritarian styles respectively.  Twenty four (4.1%) did not report on any parenting styles.

There were no statistically significant difference in the parenting styles of the college students and their socioeconomic class and gender. χ2 = 4.577; p = 0.101.  χ2 = 1.041; p = 0.904.

Conclusion: This study revealed that the commonest style of parenting among adolesents college students is the autocratic style which is in-keeping with societies with strong ethnic and cultural background. We noted no association between parenting styles with gender.

Open Access Original Research Article

Schistosomiasis Occurrence and Risk Factors Influencing Transmission in Different Surface Irrigation Schemes in Morogoro and Kilimanjaro Regions, Tanzania

Farida S. Salehe

International Journal of TROPICAL DISEASE & Health, Page 1-15
DOI: 10.9734/IJTDH/2017/30784

Aims: To assess schistosomiasis occurence and identify risk factors influencing its transmission in different surface irrigation schemes in Morogoro and Kilimanjaro Regions of Tanzania.

Study Design: Cross-sectional research design was used and Schistosomiasis recorded cases for ten years (January 2002 to December 2011) were collected from health facilities located nearby the irrigation schemes.

Place and Duration of Study: Mkindo, Chabi and Mwega (Morogoro Region) and Kikafu Chini, Lower Moshi and Njoro (Kilimanjaro Region) between October and December, 2011.

Methodology: Out of 378 respondents selected; 240 in the questionnaire survey, 96 in the Focus Group Discussions and 42 in the Key informant interviews. In each scheme 40 farmers practicing irrigation rice farming were interviewed. Binary logistic regression was used to test association between schistosomiasis infection and a number of predictors such as: age, sex, education, wearing gumboots during irrigation activities, washing clothes and household utensils and cleaning farming tools in canals. Data on activities involving water contacts, water management practices and people’s behaviour were collected through questionnaires and observations. Moreover, tables and figure were used to describe the data.

Results: There was no significant statistical association between predictors and disease occurrence in both Regions (P>0.05). The findings further show that lack of toilets in the schemes and excessive vegetation growth in irrigation and drainage canals have lead to prominence of schistosomiasis infection.  Education in both Morogoro and Kilimanjaro schemes highly contribute to occurrence of the disease (Walds 2.057 and 1.164 respectively).

Conclusion: Although the level of schistosomiasis occurance is slightly reducing in the study areas the government of Tanzania through the Ministry of Health and Social Welfare should have a plan of schistosomiasis control to communities engaged in irrigation farming and those who live close to irrigation schemes. This should be done through providing praziquantel tablets to communities at least once in a year.